Swelling of the right eyelid is usually caused by sleeping on the right side for a long time, allergies or infections, and may also be related to kidney failure, heart failure and other systemic diseases. If the patient lies on the right side for a long time, it will cause the eyelid of the right eye to be in the low-hanging part and contact with the pillow for a long time to be compressed to affect the venous blood return, which may cause the patient’s right eyelid to appear puffy, and it can be gradually subsided after getting up and moving for a period of time. Allergic patients because of contact with allergens such as pollen, hair, willow floss, etc., can appear local allergic reaction, thus causing eye swelling, patients may also appear eye itching, pain and other symptoms. Patients with eye infections such as bacterial dacryocystitis and conjunctivitis may develop eyelid edema under the stimulation of inflammation, which may be accompanied by discomfort symptoms such as photophobia, tearing and conjunctival congestion. Patients with systemic diseases such as renal failure and heart failure may also develop eyelid edema due to fluid retention, but it is usually more common bilaterally, and may appear unilaterally at the early stage of the disease. It is recommended that patients with significant eyelid edema go to the hospital in a timely manner to have their condition evaluated and treated according to the doctor’s instructions.