Low malignant potential multifocal cystic renal tumor

In the pre-2016 version, this tumor was referred to as multifoveal cystic renal cell carcinoma. The tumor consists of multihoused cysts with walls containing a single layer or clusters of clear cells without an expansile growth pattern; the morphology is indistinguishable from clear cell carcinoma (G1/2) without necrosis, vascular invasion, or sarcomatoid differentiation. It needs to be differentiated from renal clear cell carcinoma with cystic changes, extensive vitreous changes, hemorrhage, and iron-containing hemoglobin deposits. The immunophenotype is similar to that of clear cell renal cell carcinoma.