The minimally invasive McMurdo breast procedure is a minimally invasive procedure performed under local anesthesia using a vacuum-assisted rotary incision system, requiring only a small skin incision (2 mm). Typically, a biopsy probe is passed through the skin to the underside of the target mass under the guidance of ultrasound, mammogram or MRI. Under vacuum suction, the tissue is drawn into the collection tank of the biopsy probe and rotational sampling is performed until the lesion in the breast is completely or partially removed, providing the surgeon with an accurate tissue specimen for a definitive diagnosis. The procedure can be completed in 30 minutes – 1 hour. It is usually an outpatient procedure and does not require general anesthesia or post-operative sutures. After the McMurdo breast biopsy procedure, the incision is simply covered with a small Band-Aid and the patient can go home. Indications for minimally invasive breast surgery: 1, focal or suspicious microcalcifications visible on ultrasound; 2, alternative to incisional biopsy for complete removal of benign lesions such as breast fibroadenoma, breast cysts, etc. for therapeutic purposes; 3, for severe hyperplastic lesions, both diagnostic and therapeutic purposes can be achieved; 4, mammogram suggests or ultrasound shows distortion of breast structures to identify the nature of the lesion. 5.Preoperative diagnosis of highly suspicious breast malignancy; 6.Diagnosis of neoadjuvant chemotherapy or endocrine therapy before (locally advanced breast cancer) and determination of efficacy after treatment;. 7.Understand the nature of multiple lesions in other parts of the breast before breast-conserving surgery; 8.Diagnosis and treatment of new lesions around the incision after breast-conserving surgery. Contraindications to minimally invasive breast surgery: 1) Hematopoietic disorders such as bleeding tendency and coagulation disorders; 2) Pregnancy and lactation; 3) Infectious diseases; 4) Serious primary diseases such as cardiovascular, cerebrovascular, liver and kidney; 5) Psychiatric patients; 6) Suspected hemangioma of the breast; 7) Small breasts and lesions too close to the nipple, axilla or chest wall are not easy to be completely removed. 8.Patients with breast implants.