Many dots on the calf may be the manifestation of allergic purpura, eczema, folliculitis, etc., which need to be clearly diagnosed and treated symptomatically. 1. Anaphylactic purpura: It can be triggered by bacterial or viral infections, food or drug intolerance, etc. It can be manifested as red dots or soybean-sized purpura on the skin of the lower legs and other parts of the body. Most patients are treated with bed rest, oral medication and topical medication, and patients with joints, digestive tract and kidneys need to actively seek medical attention and standardized treatment. 2. Eczema: related to dietary allergies, allergies to dust, mites or clothing materials, as well as the presence of chronic inflammation in the body, etc., can appear in the calf area, manifested as red pimples, and then can be fused into a piece, with intense itching sensation. You can take loratadine, cetirizine, chlorpheniramine and other treatments, but also local application of mometasone furoate cream, dexamethasone cream, and oral prednisone and other treatments. 3. Folliculitis: mostly Staphylococcus aureus infection, manifested as multiple red spots on the calf area, accompanied by pain, redness and swelling. You can apply erythromycin ointment and mupirocin ointment locally for treatment. If there are many dots on the calf, it is recommended to consult a doctor in time, follow the doctor’s instructions for examination and treatment, and do not abuse drugs.