Tetanus bacillus invades human wounds, grows and multiplies, and produces toxins that can cause an acute and specific infection. Tetanus bacteria and its toxin can not invade the normal skin and mucous membrane, so tetanus are occurring after the injury. All open injuries have the possibility of tetanus. Etiology Tetanus is an idiosyncratic infection often associated with trauma. In addition to occurring after all types of trauma, it can also occur in mothers and newborns who deliver under unclean conditions. The organism is Clostridium tetani, which is exclusively anaerobic and Gram-stain positive. Normally present in the intestinal tract of humans and animals, with feces excretion, in the state of budding cells distributed in nature, especially in the soil is common. This bacterium has strong resistance to the environment, and can resist boiling. Etiology Clostridium tetani is an anaerobic bacterium, a conditionally pathogenic bacterium, the bacterium can only grow and multiply under anaerobic conditions or deep wounds and combined with aerobic bacterial infection. Clostridium tetani grows in mud and rust, so when the wound is deep and stained with mud or lacerated by rust-like iron, tetanus antitoxin should be injected. If only the epidermis is rubbed, the wound is not deep, as long as the proper debridement, no need to inject tetanus antitoxin. Or use some antiseptic drops such as red salve external rub can be. If the wound has dried and there is no exudate, there is no need to wipe again. Because tetanus antitoxin is a kind of immune horse serum, to the human body is a kind of heterosexual protein, with antigenicity (allergic reaction), so before the use of drugs for allergy test. If the test result is negative, tetanus antitoxin can be injected directly; if the test result is positive, desensitization injection should be performed, i.e., small doses of tetanus antitoxin should be injected in 4 – 5 times. In those who have used tetanus antitoxin for more than a week, such as re-use, but also must be re-made skin test. Tetanus is an acute specific infection caused by Clostridium tetani infesting human wounds and reproducing and producing exotoxin in the wounds, clinically the patient’s whole body or local muscle spasms and paroxysmal convulsions are mainly, Chinese medicine is also known as “tetanus”. Chinese medicine believes that this disease is caused by trauma, or infected lesions, failure to regulate, damage to the righteousness, wind evil invasion, from the surface to the inside, inducing liver wind. Modern medicine believes that the causative agent is Clostridium tetani, which is an anaerobic bacterium with positive Gram stain and is widely found in soil and human and animal feces. Clostridium tetani must invade through the skin or mucous membrane wounds, and grow and multiply locally in the anoxic wounds, producing two kinds of exotoxins, one is spasmotoxin, which has special affinity for nerves and acts on the anterior horn cells of the spinal cord or neuromuscular end plates, and causes characteristic whole-body transverse muscle persistent contraction or paroxysmal spasm, and the other is hemolytic toxin, which can cause local tissue necrosis and myocardial damage. Therefore, tetanus is a toxaemia.