Tetanus bacillus is anaerobic bacteria, in anaerobic conditions or deep wounds and combined with aerobic bacterial infection is easy to grow and reproduce (aerobic bacteria consume oxygen so that anaerobic bacteria can easily reproduce). Tetanus bacillus in the mud and rust in the common sense, this is in line with the common people, so clinically, in deeper wounds stained with mud or by rust type iron lacerations should be played tetanus injection, generally speaking, only by non-rust objects scratch the epidermis, the wound is not deep, as long as the appropriate debridement, you can choose not to play. Of course, now that medical conditions are more developed, coupled with the serious consequences of tetanus infection, more patients will mostly choose to play tetanus shots after trauma. The tetanus shot is often referred to as a way to obtain protection through passive immunity, that is, after facing a possible infection, by injecting anti-tetanus globulin, commonly used in two preparations: 1, tetanus antitoxin (TAT, from the horse). 2, human tetanus immune globulin (TIG, from human), the former requires skin testing, the latter does not require skin testing, the price is slightly more expensive, both in the tens of dollars, the general public psychological affordability. There is also a kind of protection through active immunity, that is, through the injection of tetanus toxoid, so that their own antibodies to obtain protection, here by the way to correct a misunderstanding, medical tetanus vaccine refers to tetanus toxoid preparations, from the text can also be seen, is a toxoid rather than antitoxin, and the above-mentioned TAT, TIG is often called tetanus vaccine is a common sense misunderstanding, is really a treatment The above mentioned TAT and TIG are often called tetanus vaccine, which is a common sense misunderstanding. The “tetanus” in the tetanus vaccine we often refer to is tetanus toxoid. This immunity is obtained through a series of inoculations, and its acquisition method and effective protection period is clinically complex, plus the general public has not strictly completed this procedure, or can not be confirmed, so the clinical trauma may be infected by the passive immunity is still mostly taken. The tetanus injection skin test allergy clinically refers to tetanus antitoxin (TAT, from horse) skin test allergy, can be changed to inject human tetanus immunoglobulin (TIG, from human) to obtain protection, if there is no TIG, can take TAT desensitization injection, the specific method can consult the medical staff at the consultation. If you have a history of strict vaccination, you can consult your doctor according to your condition. TAT and TIG are, of course, injected as early as possible after the injury, usually not more than 24 hours, but there is still value in injecting them afterwards (because the incubation period of tetanus infection is generally about a week, but it can develop as soon as 24 hours, so the earlier you inject them after the injury, the better). The protection time is about 2-3 days, TIG protection time is 2-3 weeks, there is no absolute clinical conclusion on this, but the approximate range, beyond this time again face the risk of infection, the need for re-injection. The protection time of active immunity obtained by tetanus toxoid injection is relatively more complicated and can be consulted with the doctor consulted, the general situation is: when injured within 3 years from the last 1 vaccination, no need to inject tetanus toxoid again, those who are more than 3 years old should be reinforced with 1 injection, for severely contaminated wounds, in addition to injecting tetanus toxoid, TAT or TIG can be injected at another site as appropriate. in fact, the ideal situation is If a person has no history of immunization, after facing possible infection, he should be injected with tetanus toxoid to obtain active immunity if the situation allows while getting protection by injecting TAT or TIG, but the clinic does not take such measures for reasons limited to individuals, hospitals, etc., and still uses TAT or TIG alone. For pregnant women, the toxicological effects of TAT or TIG are unknown, and caution is needed. However, tetanus toxoid (i.e., tetanus vaccine) is safe and is generally used in the same way as in the general population. For the prevention of neonatal tetanus, if a pregnant woman has received tetanus toxoid in the past, just one injection of tetanus toxoid in early pregnancy, at the latest 3 weeks before delivery, the antibody can pass through the placenta so that the fetus also obtains this protective antibody, and if the pregnant woman has not received tetanus toxoid in the past, another injection should be given 4 weeks after the first injection as a booster.