Korsakov’s syndrome, or alcohol-related amnesia syndrome, is one of the symptoms characteristic of chronic alcoholism. Prevention of Korsakov Syndrome Changing bad living habits, preventing alcohol abuse, and eliminating chronic alcoholism. Adopt good living habits and a nutritious diet to prevent atherosclerosis and other diseases. The course of the disease depends on the cause and is often brief. In cases of head trauma and/or subarachnoid hemorrhage, the prognosis is quite good. In cases of thiamine deficiency, such as acute necrotizing encephalitis and some other concomitant irreversible damage to hippocampal or mesencephalic structures, the prognosis is poorer and may require long-term hospital care. However, improvement may still be possible 1 or 2 years after the onset of the disease, so it is important not to institutionalize patients prematurely for chronic psychiatric conditions. Early treatment includes thiamine supplementation with adequate rehydration. If longer fluid therapy is required, special attention should be given to vitamin and caloric replenishment. There is no useful special treatment.