What is the most important treatment concern for people with epilepsy? It is when to reduce and stop the medication. This is because 80% of patients with epilepsy can have their seizures controlled with medication, and 60% of these patients remain seizure-free after stopping medication. What should epilepsy patients pay attention to when reducing and stopping their medication? 1. Patients should be completely seizure-free for more than 2-5 years under medication before they can consider stopping medication. 2. Before deciding to discontinue medication, the risk of recurrence after discontinuation must be taken into account, therefore, a discontinuation assessment should be performed before discontinuing medication. The risk of recurrence is significantly increased in the following cases: EEG is always abnormal, more seizure types, with significant neuroimaging abnormalities and significant neurological deficits. 3. The prognosis varies among syndromes, for example, in benign syndromes in children, 1-2 years seizure-free can be considered for drug discontinuation; in juvenile clonic epilepsy, even if 5 years seizure-free, the recurrence rate is high after drug discontinuation; LG syndrome may require longer treatment time. 4. The discontinuation process should be done slowly and may last for several months or even more than 1 year. 5. In case of combined medication, only 1 drug should be reduced each time, and if there is still no seizure after at least 1 month after reducing one drug, then consider reducing the second drug. 6. If a seizure occurs during drug reduction or discontinuation, the drug should be restored to the dose before the seizure.