The drug treatment of cancer pain is divided into three levels of ladder, mainly as follows: 1. non-opioid drugs, including non-steroidal drugs, adjuvant treatment of neuralgia drugs, neurotrophic drugs and sedative drugs, as the first level of medication; 2. weak opioid drugs such as tramadol, adjuvant application of non-steroidal and anti-epileptic drugs as the second level of medication; 3. when the patient’s pain is more severe, strong opioid drugs such as morphine and mescaline are selected. Auxiliary part of the treatment of neuralgia drugs and antiepileptic drugs for the third step of medication. If drug treatment is not effective, patients can be treated by nerve destruction and intrathecal morphine pump implantation, which are more effective for advanced cancer pain.