Recently, there have been some reports of adverse drug reactions that have raised concerns, which have helped to raise awareness of safe drug use among physicians and patients; they have also prompted people to think about how they can avoid adverse drug reactions as much as possible. First of all, we must realize that any drug (including devices) or even food can have adverse reactions, but we just don’t know who it will happen to, how likely it will happen, how it will behave and how serious it will be. Therefore, one of the most important principles to avoid adverse reactions is to “prescribe the right medicine”. For example, antiviral therapy for hepatitis B is a matter of opportunity and condition, and if it is not appropriate, it should not be forced. At the same time, we must also recognize that we cannot avoid treatment at any time, and that “allopathic” treatment must follow medical advice. In addition to having full knowledge of the treatment method used, the doctor must also give careful instructions to the patient, telling him/her about the precautions to be taken and the time and focus of the review. Patients should be sure to follow up on time. In some cases, it is because of the lack of standardized monitoring and review that the adverse reactions become serious. Therefore, the second important principle to avoid adverse reactions is “education” and “monitoring”.