Serpentine sores, also known as herpes zoster, is a skin damage caused by varicella-zoster virus infection, which can be treated with systemic medication, topical medication, physical therapy and other methods. 1. Systemic drug therapy: mainly choose antiviral drugs, commonly used drugs are acyclovir, famciclovir, etc.; can also be combined with sedative drugs, such as diclofenac sodium, ibuprofen, etc.; neuralgia can be combined with gabapentin, methylcobalamin and other drugs. 2. Topical drug treatment: when the blisters are not broken, you can use glycerine lotion to astringe and dry, or use antiviral drugs, such as acyclovir cream, penciclovir cream and so on. 3. Physical therapy: helium-neon laser, infrared and other local irradiation can promote the drying and crusting of blisters and relieve pain. Shingles should be actively seeking medical treatment, and all medications need to be used under the guidance of a medical professional.