Gray nails, i.e. onychomycosis, treatment mainly includes general care, local medication, and systemic administration of medication, and so on. 1. General care. Since gray nails are caused by fungal infection, they are infectious, so we must pay attention to hygiene in daily life to avoid cross-infection. 2. Local medication. Topical medication is also through the way of local rubbing, the drug through the penetration and absorption to achieve the therapeutic effect, commonly used drugs are amorphophallus powder. 3. Systemic drug treatment. Through the oral absorption of the way directly to the lesion, so as to play a strong antifungal effect, commonly used drugs are fluconazole, itraconazole and so on. Nail fungus should be diagnosed as early as possible to avoid aggravation of the condition. In order to ensure the safety and effectiveness of the drug, must strictly follow the doctor’s instructions to use the drug.