Epidural cavity hormone closure therapy is a non-surgical therapy for the rapid and effective treatment of lumbar disc herniation. The principle of action is that the hormone injected into the epidural space can eliminate the inflammatory reactions such as congestion and edema around the spinal nerve roots, loosen the adhesions around the nerve roots, counteract the sterile inflammatory exudate around the herniated nucleus pulposus, and provide pain relief. In addition, it has been confirmed with epidurography that the injected fluid can spread upward and downward in the epidural space and out along the intervertebral foramen to spread around the nerve roots. Therefore, when the injected amount of the closed fluid is large, it can generate liquid pressure, separate the adhesions between the herniated nucleus pulposus and nerve root, achieve the effect of “liquid stripping”, make the nerve root peel off from the herniated intervertebral disc tissue, release the nerve root compression and relieve the pain. At this time, the amount of closed fluid generally reaches 300 ~ 1500ml. Moreover, the anesthetic in the closed fluid can release the spasm of the lumbar muscles and relieve the muscle symptoms. Therefore, the epidural cavity hormone closure therapy can concentrate the closure solution on the local inflammation of lumbar disc herniation, play the anti-inflammatory effect of hormone, achieve the purpose of relieving the nerve root irritation and compression and treating lumbar disc herniation.