High-level lesion not excluded is the diagnostic term used for liquid-based cytology in cervical cancer screening, and high level lesion not excluded means that the presence of a high level lesion cannot be determined, but is suspected to be high level lesion. If the cytologist sees that the cervical cells are clearly highly diseased, he or she will directly report HSIL, which means highly diseased cervix, and if he or she suspects highly diseased cervix but is not sure whether highly diseased cervix exists, he or she will report ASC-H, which means high grade cervical lesion not excluded. If this diagnosis is present, supplemental HPV testing is recommended, followed by a colposcopy to determine the presence of highly diseased cervix based on the results of the colposcopy and HPV. If the colposcopic HPV test is highly suggestive of high-grade lesions, a cervical biopsy is recommended, and the next step in treatment will be based on the biopsy results. If the HPV is negative, and no high-grade lesions are seen on colposcopy, cervical aspiration and cervical biopsy can be performed to further rule out the presence of high-grade lesions, and if the pathology is still suggestive of high-grade lesions, treatment will also need to be done. If the biopsy, cervical tube scratching suggests no lesions, you can periodically review the liquid-based cytology, temporarily exclude the possibility of highly pathologic lesions.