Poor sleep is difficult to improve with vitamin supplements. Poor sleep requires a clinic visit first to determine the cause and target treatment. Because B vitamins have some benefits in supporting nervous system function, some vitamin B1 and vitamin B6 are often given along with clinical adjuncts. Vitamin B1 and vitamin B6 are important nutrients for maintaining nervous system function. Both are involved in the formation of coenzymes in the body, which can maintain normal glucose metabolism and the function of the nervous and digestive systems. For patients with insomnia, medications such as diazepam, lorazepam, and dexzopiclone are often used after the cause of the condition has been identified. If necessary, it can be combined with fluoxetine, venlafaxine and other drugs to improve depression, anxiety and other symptoms. When long-term sleep is not good, it is recommended to consult a doctor in time, standardized diagnosis and treatment. In addition to medication under the guidance of the doctor, in daily life should pay attention to the combination of work and rest, do not have too much pressure, learn to regulate pressure, maintain a relaxed mood. Appropriate physical exercise can be done to promote blood circulation in the body. Good work and rest and living habits can help improve the quality of sleep.