Total removal of the large intestine will not affect life expectancy if there are no obvious complications, but due to the loss of the physiological function of the large intestine, complications may occur and care should be taken. The physiological function of the large intestine is to absorb water and a small amount of vitamins from food waste, but since the main nutrients needed by the body, such as proteins and fats, are absorbed in the small intestine, the total removal of the large intestine will not affect life expectancy. However, total removal of the large intestine may lead to diarrhea, some patients may develop intestinal adhesions, and even abdominal distension and pain, etc. If abnormalities occur, you should consult a doctor in time for treatment. In addition the diseases that lead to total removal of the large intestine can have a significant impact on life itself and should be considered. After total removal of the colon, there is usually no need to be overly nervous, you can usually consume light, low-fat food, and keep the incision clean to prevent infection. After total removal of the colon, if any abnormalities occur, you should seek medical attention.