Infantile spasms, also known as West syndrome, is the most common age-dependent epileptic encephalopathy of infancy. Clinical manifestations: The typical clinical manifestations can be graphically described as nodding, harassing, and hugging in bunches of seizures. The early stage may be atypical, without string seizures, or with only nodding spasm-like movements. Close follow-up is required. EEG: The EEG between seizures in infantile spasms is characterized by peak rhythm disturbances. Peak rhythm disturbance is more pronounced during sleep. During infantile spasms, the peak rhythm disturbance disappears and the EEG may show high amplitude slow waves or spike-slow wave bursts, and/or extensive low voltage fast waves. 2.Other auxiliary examinations Neuroimaging examinations such as CT, MRI, PET, SPECT can assist in detecting structural or functional lesions in the brain. If necessary, tests related to congenital metabolic diseases may be performed. Treatment: The disease seriously affects the quality of life of the child. Early control of seizures is important to improve the prognosis of the child. The first-line drug for this disease is hormone therapy. At present, the main drugs for the treatment of infantile spasms in China are ACTH, sodium valproate, clonidine, topiramate, vitamin B6 and levetiracetam.