Gastroscopy is usually possible after kidney transplantation if the patient is stable. After kidney transplantation, if the patient’s condition is stable, usually can do gastroscopy, also can do painless gastroscopy. Painless gastroscopy requires anesthesia, the metabolism of anesthesia drugs in the body, although most rely on liver metabolism and renal excretion, but the routine dose of anesthesia drugs will not damage the patient’s renal function, there is generally no harm, and painless gastroscopy can reduce the pain and psychological burden. The absolute contraindication groups of gastroscopy include patients with severe cardiopulmonary diseases, suspected digestive perforation, acute inflammation of the digestive tract, mental illness, stroke patients, and patients with obvious thoracic and abdominal aortic aneurysms, etc. If the patient is accompanied by one of the above conditions, the patient can be treated with anesthesia. If the patient is accompanied by one of the above conditions at the same time, gastroscopy cannot be done. To summarize, it is recommended that patients seek medical advice and cooperate with the doctor’s examination and treatment.