It is like having small worms in the anus, which refers to the feeling like worms wriggling in the anal area, and may be related to parasitic infections, hemorrhoids, perianal eczema, perianal abscess, etc.; it can be relieved by life management, medication, and surgical treatments according to the cause of the disease. 1. Parasitic infections: If the patient has parasitic infections such as pinworms and roundworms, it may lead to perianal itching and the sensation of crawling worms. Pinworms can be treated by oral medication such as thiopyridine and thiopyrimidine; roundworms can be treated by oral medication such as mebendazole and albendazole. 2. Hemorrhoids: hemorrhoids will appear local skin itching, pain, bugs crawling and other feelings, can be oral hemorrhoids fast Ning tablets, Mai Zhi Ling tablets and other drugs, with the use of hemorrhoid cream coating, severe cases can be through the external peeling and internal ligation and other methods of treatment. 3. Perianal eczema: patients with perianal eczema will have obvious itching, skin hypertrophy, ulceration and other phenomena, patients may have the illusion of crawling insects. Local application of tretinoin cream, glycerite lotion and other drugs to relieve, if necessary, with oral chlorpheniramine, ipecac and other drugs. 4. Perianal abscess: Once the perianal abscess is formed, there will be obvious pain and itching symptoms, and patients can hardly sit still. It is necessary to timely pass through the surgery, the abscess cut, the inside of the decayed tissue clean up. Patients with the above symptoms, should consult a doctor in a timely manner, first to clarify the cause of this symptom, and then according to the cause, strictly comply with the medical advice to use drugs, surgery or other methods of treatment, can not blindly use their own medication, to avoid delaying the condition.