LVNC varies in clinical presentation and severity, from fetal to geriatric age, asymptomatic or end-stage heart failure, fatal arrhythmias, sudden death, thromboembolism, or a combination of clinical manifestations. Many asymptomatic patients are diagnosed by a heart murmur, or by a diagnosis in a family screening for LVNC, or by arrhythmia or conduction block. Ichida reported almost asymptomatic and good survival in children, with few deaths or heart transplants, whereas chin reported 3 out of 7 deaths. towbin JA reported that although neonates and small infants are often clinically critical and have high mortality due to concomitant systemic diseases such as mitochondrial disease or genetic metabolic disorders, LVNC in children 18 months to 3 years of age has been associated with a high mortality rate. The prognosis for LVNC in children 18 months to 3 years of age is good, with a 5-year non-cardiac transplant survival rate of 75%. There are several reports of a high risk of ventricular tachycardia and sudden cardiac death in adults with LVNC. In adult patients, mortality was 47% within 6 years from diagnosis and 75% within 6 years in symptomatic patients.Bhatia et al. reviewed 241 cases of ultrasound-diagnosed isolated LVNC with 39 months of follow-up, with 4% cardiac death per year, 6.2% cardiac death, heart transplantation and ICD implantation combined, and 8.6% cardiac events per year overall (death, stroke, ICD, shock, heart transplantation ). First-degree relative ultrasound screening for LVNC accounts for 30%. The rate of malignant ventricular arrhythmias in LVNC is uncertain, but reports of benign process LVNC and lower ventricular arrhythmia rates have increased significantly in recent years. The morphology and increase in ventricular myocardium is the key to diagnosis, and there are two clinical diagnoses of isolated LVNC and combined preexisting LVNC. the clinical manifestations of LVNC are diverse and vary greatly in severity, and it is the fact that not many people have ventricular myocardium that meets the diagnostic criteria for LVNC but has no clinical symptoms throughout their lives that reduces the importance clinicians attach to increased myocardial myocardium, which in turn affects poor prognosis Early diagnosis and intervention in patients with LVNC seriously affects the prognosis. the diagnostic ideas of 8 LVNC subtypes proposed by Towbin JA deserve our consideration. Giving reasonable follow-up to patients who meet the diagnostic criteria of LVNC by ultrasound, set large data in order to address the current situation of overdiagnosis or underdiagnosis of LVNC and avoid malignant prognosis in high-risk LVNC patients. In our work there is the same knowledge that not only the following 8 types of staging exist, but also mixed types or called unknown classification. (1) Benign LVNC: The absence of enlargement of the left ventricle, no wall thickening, and normal ventricular systolic-diastolic function is called benign LVNC, accounting for about 35%. The prognosis is good if no arrhythmia is present. For this type, some adult cardiologists consider that it cannot be classified as heart disease and is a normal variant. In other words, most of the severe clinical manifestations of LVNC occur in children who are either successfully cured, have a heart transplant or die, mostly without visiting an adult cardiologist. Benign LVNC can be classified as normal, but should be given standardized follow-up. (2) Arrhythmogenic LVNC: LVNC with arrhythmia has normal left ventricular size, systolic function, and ventricular wall thickness. However, the arrhythmia is insidious, and the diagnosis is given only when the arrhythmia is mostly present. Ventricular arrhythmias are an independent risk factor for death. The prognosis of LVNC with arrhythmias is worse than that of ventricular arrhythmias without LVNC. Emphasis on ultrasound screening of LVNC is easier to diagnose. (3) Dilated LVNC: The dilated subtype of LVNC is an enlarged ventricle with poor left ventricular systolic function. The clinical course can present with ventricular wall thickening and normal cardiac function, which later progresses to ventricular enlargement and decreased cardiac function. The prognosis of dilated LVNC in adults is similar to that of dilated cardiomyopathy of unknown origin. However, the prognosis of dilated LVNC in neonates and infants is worse than that of other dilated cardiomyopathies, which may be related to the coexistence of genetic metabolic diseases and hereditary arrhythmias. (4) Hypertrophic LVNC: Hypertrophic LVNC is characterized by thickened left ventricular wall, asymmetric septal hypertrophy, diastolic restriction, and excessive systolic enhancement. In some cases with LV dilatation, systolic insufficiency can occur in late stages. The prognosis is similar to that of hypertrophic cardiomyopathy. (5) Hypertrophic dilated LVNC: The clinical manifestations are varied, showing thickening of the left ventricular wall, ventricular enlargement, and systolic insufficiency. This type has a high mortality rate, and pediatric patients are often combined with genetic metabolic disease or with mitochondrial disease. Hypertrophic dilated LVNC is the most common type of LVNC with variable symptoms and results in enlarged left heart, cardiac insufficiency, and heart failure. This type has the worst prognosis compared to other mixed LVNC types. (6) Restrictive LVNC: It is rare and presents with left atrial or biventricular enlargement and diastolic insufficiency. The clinical symptoms and prognosis are very similar to those of restrictive cardiomyopathy, and the prognosis is poor. Typical cases are at high risk of sudden arrhythmic death and less frequently death from heart failure. (7) Right ventricular or biventricular LVNC: As the name implies, right ventricular LNVC or biventricular LVNC, but there is no clear diagnostic criteria for right ventricular LVNC, and some literature reports the application of diagnostic criteria for left ventricular LVNC.JA Towbin et al. diagnosed with a marked increase in myocardial trabeculae in the right ventricle, similar to sponge-like. In most of these cases, the myocardial trabeculae involved the right ventricular lateral wall and even extended to the level of the tricuspid valve. Biventricular LVNC is rare and clinically unclear. (8) LVNC with congenital heart disease: Almost all kinds of congenital heart disease have been reported with LVNC, which can lead to cardiac insufficiency and arrhythmias, or both. Congenital right heart structural abnormalities are more common, especially Ebstein’s malformation, pulmonary stenosis, pulmonary atresia, tricuspid atresia, and double outlet of the right ventricle. Septal defects or left heart dysplasia are also common. Prognosis is dependent on cardiovascular anomalies. However LVNC increases the postoperative risk with the presence of preoperative heart failure and a poor prognosis. [5] Having a diagnosis of benign LVNC facilitates interpretation to patients with asymptomatic LVNC and gives a more rational clinical diagnostic pathway and follow-up protocol.