Tamoxifen mostly refers to tamoxifen citrate tablets, without bone metastasis, calcium tablets and tamoxifen citrate tablets usually take which one first; those who have bone metastasis, it is recommended that tamoxifen citrate tablets should be taken first, and the specifics need to be followed by the doctor’s instructions. Tamoxifen Citrate Tablets is a non-steroidal drug with anti-estrogenic effect, which is suitable for recurrent or metastatic breast cancer, and postoperative adjuvant treatment of early breast cancer. Since some breast cancer patients with bone metastases develop hypercalcemia during the first few weeks of the drug’s use, it is usually recommended to take tamoxifen citrate tablets first in order to prevent aggravation of the disease by taking calcium tablets. When consuming tamoxifen citrate tablets for patients with bone metastasis, they also need to check their blood calcium regularly, and should consume calcium tablets only if their body has calcium deficiency. For patients with non-bone metastases, either calcium tablets or tamoxifen citrate tablets can generally be taken first, although it is necessary to determine whether there is a calcium deficiency before consuming calcium tablets. Tamoxifen Citrate Tablet side effects such as vaginal bleeding, increased discharge, vulvar itching, menstrual disorders, rash and headache are possible during the use of the drug. This drug is contraindicated in pregnant women, those who are planning pregnancy, those who are allergic to this drug, those who have fundopathy, and should not be used in combination with anastrozole. Calcium tablets should not be taken in excess. Patients should follow the instructions of their medical professionals when taking both Tamoxifen Citrate Tablets and Calcium Tablets.