The cranium is a vital organ in the human body and plays an important role in protecting and supporting the brain and the organs of the head and face. However, there are many risk factors in life that may damage the skull, and patients with skull defects are often seen in neurosurgery clinics. Cranial defects can have a serious impact on the aesthetic appearance and neurological function of the patient’s skull, and therefore require timely cranial bone repair. Is peek material cranial bone repair technology mature? Cranial bone repair is a relatively routine operation in neurosurgery, which is widely carried out in clinical practice. The purpose of cranial bone repair is to restore the complete and closed cranial cavity environment and repair the neurological damage on the one hand; on the other hand, the important purpose is to restore the aesthetic appearance of the skull. However, traditional cranial bone repair using titanium mesh or other materials, it is difficult to do a good shape, the repair may not be able to shape the beautiful symmetry. But the good news is that there is a new type of polyether ether ketone PEEK material, which can be used to produce a highly conforming cranial bone structure of the repair plate through three-dimensional reconstruction and 3d printing technology, with good molding effect. A large number of clinical practice has proved the advantages of polyether ether ketone (PEEK) material, polyether ether ketone (PEEK) material, this polymer material is almost comparable to the performance of the human cranium, it is strong but very elasticity and toughness, has a high degree of biocompatibility, high resistance to impact, good protective performance. And polyether ether ketone (PEEK) material basically does not conduct heat, has a high thermal insulation performance, there will be no postoperative infection, there will be no rejection.