If the pain in the back is aggravated during inspiration, there are several clinical reasons: 1. inflammation of the pleura, when the thorax expands during inspiration, if inflammation of the pleura occurs, it can lead to pain in the back during deep inspiration. 2. intercostal neuralgia and chondromalacia, because the ribs will be elevated during inspiration, if there are episodes of intercostal neuralgia and chondromalacia, it can lead to aggravation of pain in the back. 3. lung Lesions can also lead to back pain during deep inhalation, because the lungs fill up during inhalation, and if there are lung infections, lung tuberculosis, lung tumors and other diseases, it can lead to back pain during deep inhalation. 4. Herpes zoster of the skin can also lead to back pain during deep inhalation.