The normal range of bilirubin in newborns should be between 5-7mg/dl. If this range is exceeded and the bilirubin in the child’s body is too high, it can cause yellow skin visible to the naked eye, called jaundice. Among the main causes of jaundice, the first one is caused by intrauterine infections during the mother’s pregnancy, of which the most common pathogens are Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus and other hepatophilic viruses such as the EBV, among others. Of these, the more common is cytomegalovirus, which is found replicating in the mother’s breast milk when it is checked after the birth of the child. In this case, breastfeeding is usually stopped and active antiviral treatment is given. The second, neonatal hemolytic disease, this condition appears jaundice is generally faster, more acute, also more serious, must be actively treated. If neonatal sepsis is a serious infection, it can also affect the metabolism of bilirubin, which increases bilirubin and causes jaundice.