The standard regimen of chemotherapy for seminomas is cisplatin, there is no clinical study on the comparison of carboplatin and cisplatin dosing to determine which is more effective, and chemotherapy should be treated symptomatically. Seminoblastoma can be chemotherapy according to the stage, in the way recommended in the clinical guidelines, is a program containing cisplatin, according to the patient’s body surface area to calculate the dose of cisplatin. Carboplatin and cisplatin both belong to the platinum group of drugs, the anti-tumor spectrum between the two are different, no cross-resistance, in the use of cisplatin is ineffective, or the adverse effects can not be tolerated, you can consider replacing carboplatin. The most obvious side effect of applying cisplatin is digestive tract reaction, such as nausea, vomiting, anorexia, loss of appetite, etc., and attention should be paid to hydration, diuresis and antiemetic treatment at the same time of using the drug. It is contraindicated for those who are allergic to the product. Therefore, it is impossible to simply say whether it is better to use carboplatin or cisplatin, and a review should be conducted after chemotherapy to evaluate the effect of treatment.