Aminotransferases are often listed as a medical test. Some people have high aminotransferases and are very frightened. Aminotransferases mainly include glutamate transaminase and glutamic oxalacetic transaminase. Among them, ALT is mainly found in the liver and AST is found in large quantities in the heart, skeletal muscle and other organs. When the cells of these tissues and organs are damaged, transaminases are released into the bloodstream, and serum transaminases are elevated. The normal value of transaminases is usually 0-40 U/L. The value varies from laboratory to laboratory depending on the test method and instrumentation. About 2.5% of the healthy population has mildly elevated blood transaminases, and the results may be different at different times of the day. For example, strenuous exercise, overexertion, or eating fatty foods or taking certain medications before the test may cause transaminases to be temporarily and mildly elevated. In these cases, take a good rest and have the test done again after a period of time, and the transaminase level may be normal. However, if transaminases continue to rise, it is important to pay attention to them. There are many common causes of high aminotransferases: 1. Viral hepatitis: is a common disease that causes high aminotransferases, mainly including hepatitis A, B, C, D and E. Some, such as EBV and cytomegalovirus, can also cause elevated aminotransferases. Liver cirrhosis and liver cancer can also cause high aminotransferases in some patients. 2, drug liver damage: certain drugs or chemical agents such as anti-tuberculosis drugs, chemotherapy drugs, erythromycin, sleeping pills, antipyretic and analgesic drugs, contraceptives, and certain Chinese medicines for psoriasis can cause liver cell damage. After discontinuing these drugs, the transaminase level will return to normal. 3, alcoholic liver disease: long-term heavy drinking, generally refers to more than 5 years, the amount of equivalent ethanol ≥ 40g / d for men, women ≥ 20g / d; or a history of heavy drinking within 2 weeks, the amount of equivalent ethanol > 80g / d. The amount of ethanol (g) conversion formula = the amount of alcohol (ml) × ethanol content (%) × 0.8. 4, fatty liver: alcoholism, obesity, three high people, sedentary people with little movement, are likely to The presence of fatty liver. 5, autoimmune hepatitis: common in women, often accompanied by other symptoms such as dry mouth, dry eyes, hair loss, light allergy, joint pain, etc. 6, biliary tract diseases: such as cholecystitis, gallstone acute attacks, in addition to fever, abdominal pain, nausea, vomiting, jaundice, etc., can also cause high transaminases and bilirubin. 7, heart disease: such as acute myocardial infarction, myocarditis, heart failure, can cause high aminotransferases. 8, other diseases: such as pneumonia, typhoid, infectious mononucleosis, leptospirosis, schistosomiasis, trematode, malaria, etc., can also cause high aminotransferases. In short, high aminotransferase is not necessarily a liver problem, do not blindly take enzyme-lowering drugs, to find out the cause of its elevation, in order to effectively treat.