Treacher-Collins syndrome, also known as maxillofacial hypoplasia and deafness syndrome, has no specific treatment but can be treated symptomatically to improve the patient’s symptoms. The cause of the syndrome is unknown, but it is a multiple facial anomaly syndrome, mainly due to structural abnormalities in the differentiation of the first gill arch. Currently there is no drug can be completely treated, you can follow the doctor’s advice symptomatic treatment, in order to improve the quality of life. Bird-face syndrome does not affect the function of human organs in most cases, and is dominated by facial deformities. Therefore, the quality of life of patients can be improved through facial orthopedic treatments, such as orthopedic lips and mouth, improvement of articulation, and intubation when respiratory tract obstruction occurs. Due to facial deformities, patients may have psychological problems, and attention should also be paid to interventional therapy to correct low self-esteem.