Postoperative pathology of intestinal polyps suggests high-grade intraepithelial neoplasia, endoscopic resection should be performed, and after resection, the presence or absence of invasive carcinoma should be clarified, and if so, radical surgery should be performed. High-grade intraepithelial neoplasia refers to severe atypical hyperplasia, which is a kind of precancerous lesion, mainly carcinoma in situ, that is to say, early carcinoma has already appeared, but invasive carcinoma has not yet occurred. But it needs to be taken very seriously. If high grade intraepithelial neoplasia is found, resection of the lesion should be performed in time, and after resection, pathological examination should be perfected to see whether infiltration occurs, and if infiltration occurs, it is necessary to treat it again, for example, to perform radical surgery, and if necessary, it is also necessary to have radiotherapy and chemotherapy after surgery. After the operation, the relevant indexes need to be reviewed regularly to monitor whether there is any metastasis, etc., in accordance with the doctor’s instructions.