Cough, as a clinical symptom, cannot cause supraclavicular lymph node enlargement by itself, but the disease causing the cough may cause supraclavicular lymph node enlargement. 1. Conditions that do not cause lymph node enlargement may be gastroesophageal reflux disease, cough variant asthma and other diseases. Although these diseases can cause coughing symptoms, the diseases themselves do not involve the lymph nodes and do not cause supraclavicular lymph node enlargement. 2. The condition that can cause supraclavicular lymph node enlargement may be the cough caused by infection, especially in patients with pulmonary tuberculosis, which may be accompanied by lymph node involvement, appearing in the hilar mediastinal lymph node enlargement. It even leads to cervical lymph node tuberculosis and so on, which triggers cervical lymph node enlargement. Besides that, patients with lung cancer or lung metastatic cancer can also lead to the occurrence of cough, and patients with lung cancer can have lymph node metastasis, which may also lead to supraclavicular lymph node enlargement.