Peripheral nerve injury after chemotherapy for multiple myeloma can be relieved by adjusting chemotherapy program, medication, heat application, physiotherapy and other treatments to relieve peripheral neuropathy. 1. Adjusting chemotherapy program: if peripheral nerve injury occurs after chemotherapy, it is necessary to stop chemotherapy or change the drug dosage, consult the doctor to change the chemotherapy program, adjust the type and dosage of chemotherapy drugs, etc. Specific chemotherapy drugs include bortezomib, lenalidomide and other drugs. Specific chemotherapy drugs include bortezomib, lenalidomide, cyclophosphamide, dexamethasone and so on. 2. Drug therapy: Nutritional nerve drugs can be used to repair damaged peripheral nerves, and the drugs of choice include methylcobalamin, B vitamins, nerve growth factor, etc. Glutathione antioxidant can also be used to promote nerve repair. If neuropathic pain occurs, amitriptyline, tramadol, ketamine and so on can be used to relieve pain. 3. Hot compresses: Use hot towels or hot water bags to apply localized hot compresses on the damaged parts of the nerves to promote blood circulation and accelerate nerve repair. 4. Physiotherapy: acupuncture treatment, infrared ray baking lamp, ultra-short wave treatment can also relieve the peripheral nerve damage caused by multiple myeloma chemotherapy. If peripheral nerve damage occurs after chemotherapy for multiple myeloma, it is recommended to go to the hospital in time and be treated by specialists according to the specific situation. The above medications should be used under medical supervision.