The symptoms of peripheral nerve injury mainly include numbness and weakness of the extremities. Patients mostly show symptoms of weakness and numbness from the distal extremities of the lower extremities, which can gradually develop proximally. Patients may exhibit sensory abnormalities such as insect sensation, burning sensation, pins and needles sensation, cutting sensation, etc., and the damage is usually bilateral and symmetrical. In addition, symptoms such as skin pigmentation and muscle atrophy may occur. Peripheral nerve damage is often caused by diabetes, tumors, drugs, poisoning, infection, etc. Patients need to go to neurology for relevant examination and treatment to clarify the cause. The examination means mainly include blood routine, blood sugar, tumor markers, electromyography, MRI, etc. If necessary, muscle biopsy and other tests should be performed to clarify the diagnosis.