1, pay attention to safety Treatment of hepatitis B drugs should first emphasize safety, hepatitis B patients are prone to change, the course of treatment is long, a single drug is difficult to achieve the purpose of treatment, now more than the use of combination therapy, drug safety is the first priority. Many of the hepatitis drugs used years ago were later proven to be unsafe, such as adenosine and phosphonate, all of which may cause renal impairment. Interferon and lamivudine, which are currently in use, also have serious safety concerns and may lead to exacerbation if used improperly, selected improperly or discontinued without permission. Chinese medicines also have the same unsafe factors. Some herbs and herbal preparations have been proven to have significant liver-damaging effects, such as the herbs Cang Er Zi, Guan Zong, Lei Gong Vine, Smallpox Powder, Nutmeg, Peppermint, Neem, etc.; the proprietary Chinese medicines include Xiao Chai Hu Tang, Compound Qing Dai Wan, Nucleus Elimination Tablets, Ke Yin Wan, etc. Therefore, it is important to avoid abuse and overdue, overdose, for folk prescriptions, prescriptions must be used with caution to prevent poisoning. Patients with a history of drug allergy or allergic constitution, once the drug liver damage, must terminate the use of the drug, go to the regular hospital for treatment in a timely manner. 2, the pursuit of effectiveness Now many of the old drugs for hepatitis B, such as oral famciclovir, acyclic guanosine, etc. have been proven to be ineffective and are now gradually eliminated. At present, as the main drug for the treatment of hepatitis B – anti-hepatitis B virus drugs, recognized only interferon, lamivudine and several other drugs labeled as having anti-hepatitis B virus nature, has not yet been unanimously recognized. In addition, hundreds of so-called “hepatoprotective drugs”, only some of them have the effect of improving liver function and reducing the inflammatory response of the liver. So patients must choose their medications carefully, and must not be rash or reckless, and must not believe in advertising and other propaganda. 3, advocate economy Treatment of hepatitis B costly, expensive drugs is well known, hepatitis B patients with erratic disease, medication constantly, many patients due to the disease to poverty. Therefore, hepatitis B patients must be careful with their medication and spend less money. For example, there are many drugs with liver-protecting and enzyme-lowering functions, so when choosing a drug, you must take into account your affordability and compare them with other drugs, such as Ganixin injection, which are inexpensive and good value. Many new drugs have undetermined long-term efficacy, plus the price is very expensive, should not be recommended as a first-line drug trial. (1) Appropriate drugs According to the disease and the condition of the patient’s body, weigh the advantages and disadvantages of various factors and choose the most appropriate drugs of the same kind. For example, in patients with early cirrhosis, antiviral drugs combined with anti-fibrotic drugs are most effective when used simultaneously. (2) The appropriate dose of interferon for the treatment of hepatitis B is very common, and the dose is very delicate to grasp. If the dose is too small, it is difficult to work; if the dose is too large, the drug toxic effect is too strong, the patient’s body can not bear. It is generally believed that the appropriate dose for Chinese people is 5 million to 6 million units / every other day 1 time use. (3) Appropriate time for example, long-acting interferon used once a week can ensure that the drug concentration in the patient’s blood basically remains within the effective range within a week, which can give the patient less pain and trouble. (4) The appropriate route of administration must take into account the purpose of the drug, the nature of the drug, the patient’s physical condition, as well as safety and economy, simplicity and other factors. Oral administration is both convenient and economical, and the patient suffers less pain, on the contrary, intravenous drip is not advocated to be used easily. (5) appropriate patient treatment of hepatitis B emphasizes the principle of individualization and individualized treatment, such as interferon treatment, must require the condition of patients with elevated transaminases and positive hepatitis B virus replication indicators; severe or heavy hepatitis B patients should not be treated with interferon. (6) The appropriate course of treatment in accordance with the principles of therapeutics, specify the cycle of drug therapy. Both anti-hepatitis B virus treatment and anti-liver fibrosis treatment require long-term persistence. When the efficacy is obvious, the medication should not be stopped without authorization, and the treatment should be prolonged if necessary to obtain stable and lasting results. For example, the treatment of hepatitis B with lamivudine and interferon requires a course of treatment of more than 1 year. Some drugs, however, should not be used for a long period of time, and it is important to avoid prolonging the administration time to reduce the appearance of adverse reactions such as accumulation poisoning, viral resistance, and drug dependence. For example, once a hepatitis B patient has a cold and fever, the use of anti-inflammatory drugs must take the principle of “short and quick”, so that the disease can stop the drug.