Lung adenocarcinoma oozing edema can be treated on the basis of treating the primary disease, including drug treatment, radiotherapy, stereotactic radiotherapy and so on, and the use of drugs should be in accordance with the doctor’s prescription. Lung adenocarcinoma oedema is mostly related to hypoproteinemia, malnutrition, superior vena cava compression, pelvic space occupation, etc. First of all, patients should be actively treated for the primary disease, i.e. lung adenocarcinoma treatment, including surgery, radiotherapy, chemotherapy and targeted therapy. Oedema in lung cancer patients also depends on the site and cause of oedema, if it is double lower limbs oedema, consider hypoproteinemia and malnutrition, and can be treated with supplemental albumin plus diuretics, diuretics such as hydrochlorothiazide. If it is combined with unilateral pleural effusion, the pleural effusion can be drained, and chemotherapeutic drugs or anti-tumor angiogenesis drugs can be instilled in the thoracic cavity to reduce the pleural effusion, such as cisplatin. If the edema of both upper limbs is considered to be superior vena cava compression, radiotherapy or simultaneous radiotherapy for the mediastinal tumor may reduce the compression of the superior vena cava by the mediastinal tumor, which may help to alleviate the symptoms of edema. If the tumor has metastasized to the pelvis and caused pelvic space-occupying lesions that lead to double lower limb movement disorder, local stereotactic radiotherapy for pelvic space-occupying lesions can help to alleviate the symptoms of edema. It is suggested that patients with lung adenocarcinoma edema should go to the hospital in time to avoid delaying the disease.