There are many causes of ankle pain, the common ones are bone and joint tumors, metabolic diseases, bacterial infections, arthritis, external forces, etc., as follows: a. Bone and joint tumors: the presence of benign bone tumors or malignant bone tumors will lead to significant pain symptoms in the ankle. Metabolic diseases: The presence of gouty arthritis can lead to swelling and pain, and is often accompanied by morning stiffness. Bacterial infection: If the patient has local bacterial infection, which leads to osteomyelitis and septic arthritis, it will also lead to obvious pain symptoms in the ankle. Arthritis: If the patient has rheumatoid arthritis or osteoarthritis, it will also cause painful symptoms. External force: If the ankle joint is subjected to external force, causing local soft tissue injury, ligament tear, fracture or dislocation, it will also lead to obvious pain symptoms in the ankle.