Soreness in the ankle can be caused by the following diseases: First, osteoarthritis, a degenerative bone change, occurs more often in elderly patients, you can choose local physiotherapy methods of heat compress, massage, if necessary, you can also take oral pain medication, the application of aminoglutethimide tablets or nimesulide dispersible tablets. Usually, you should also pay attention to not to bear weight and strain, but you can do sports and exercise properly. Secondly, some patients are caused by venous system diseases, commonly varicose veins in the lower limbs, with the development of the disease will lead to the distal vasodilatation aggravated, and even the formation of thrombophlebitis, but also the pigmentation of the foot and boot area into obvious pain, aggravated after activity. Patients with mild cases are mainly treated conservatively by elevating the limb to promote venous blood return. It can also be treated by wearing compression stockings during activity, and in severe cases surgery is an option.