Contraindications to atropine eye drops include glaucoma or glaucomatous tendency, tachycardia, and asthma. The main effect of atropine is to dilate the pupil, and the use of atropine drops in patients with glaucoma or glaucomatous invasion tendency will lead to the blockage of the angle of the atrium to make the glaucoma condition worsened, with dizziness, headache, and nausea and vomiting, as well as a rapid decline in vision and other symptoms. Therefore, patients suffering from glaucoma should not use atropine. Atropine is a drug that makes the heart beat faster. If the patient has tachycardia, its use may make the heart beat faster and increase the burden on the patient’s heart. It should not be used when a patient has an arrhythmia and a fast heart rate. Although atropine can relieve smooth muscle spasm, but at the same time inhibit the secretion of glands, so that the phlegm is sticky and not easy to cough up, thus aggravating bronchial obstruction, leading to increased inflammation, and can not relieve bronchial asthma. Therefore, patients with bronchial asthma can not use atropine. It is recommended that patients use atropine eye drops under the guidance of a doctor, do not use without authorization to avoid causing adverse reactions.