After 24 hours of cephalosporin injection can not drink alcohol, drinking alcohol during the medication will affect the drug absorption and effect, increase the side effects of drugs, some cephalosporin drugs will produce disulfiram-like reaction. 1. Influence drug absorption and effect: alcohol can affect drug absorption and liver metabolism, which in turn affects the drug effect, leading to poor disease control, prolonging the course of the disease. 2. Increase side effects: Alcohol can also aggravate the side effects of Cefdinir, increase the risk of abdominal pain, diarrhea, skin rash and other side effects, and may also increase liver and kidney function damage. 3. disulfiram-like reaction: most often seen in the molecular structure of the drug and disulfiram molecular structure similar to the existence of the active group of thiomethyl tetrazolium, in the use of alcohol during the use of drugs can be weak, dizziness, drowsiness, hallucinations, generalized redness, headache, nausea and vomiting, decreased blood pressure, and even shock and other reactions. These include cefoperazone, cefmetazole, cefmenoxime, cefotiam, and radox cephalosporin. Therefore, it is not recommended to drink alcohol during the use of the drug and 1 week after the use of the drug, the side effects of alcohol consumption can be life-threatening in severe cases, and it is necessary to strictly limit the intake of alcoholic beverages. The medication should be used under the guidance of a professional physician, and should not be used arbitrarily on its own.