The interval between the 13-valent pneumonia vaccine and the Pentavalent vaccine is usually about one month. The 13-valent pneumonia vaccine is designed to prevent pneumococcal infections, while the Pentavalent vaccine is designed to prevent whooping cough, Haemophilus influenzae, diphtheria, poliomyelitis and tetanus. There is a time overlap between the two vaccine regimens, and because of their different roles, it is generally prudent to vaccinate about one month apart. If a child has a fever, cold or diarrhea before receiving the 13-valent pneumonia vaccine or the pentavalent vaccine, it is not appropriate to receive the vaccine, and the child should be vaccinated one week after recovering from the illness. After vaccination, parents should observe their children to see if there are any adverse reactions such as rash or fever, and if there are any adverse reactions, they should go to the vaccination unit for review in a timely manner. If symptoms of discomfort occur after vaccination, you need to go to the hospital in a timely manner, with the doctor to give the appropriate treatment and treatment, so as to avoid adverse consequences.