With the arrival of summer, all kinds of bugs are active, and there are reports of fatal bug bites in the wild, so people can’t help but feel alarmed: small bugs are fierce! Summer travel peak season is approaching, people travel to enjoy the beautiful scenery of nature at the same time, do not forget to do a good job of personal protection in the field to prevent insect damage. Insects are diverse and varied, and are the most numerous animal group on earth. Common insect species include bees, wasps, fleas, reptiles, mulberry caterpillars, pine caterpillars, bedbugs, ants, lice and beetles. Common arachnids include spiders, scorpions, ticks, and mites. Insects and arachnids account for almost more than half of the proportion of known species in existence and represent 90% of the biodiversity on Earth. Therefore, human exposure to these organisms is inevitable, and stings can be almost imperceptible and life-threatening. severe local pain, edema, petechiae, and even necrosis, and in severe cases, systemic allergic reactions, shock, hemolysis, muscle damage, nerve paralysis, loss of consciousness, convulsions, etc., and even multi-organ failure and death. The specific IgE antibodies in human body cause allergic reactions when they interact with different bee venoms. If the bee stings again, the bee venom enters the sensitized body as an allergen and combines with IgE on the mast cell and basophil membranes to release histamine and eosinophil chemotactic factors, causing smooth muscle spasm, vasodilation, increased microvascular permeability, and tissue edema, often manifesting as itching, erythema, and urticaria. The main symptoms of urticaria are itchiness, erythema, and puffiness, and in severe cases, angioneurotic edema and anaphylaxis. The main reason for this is the fact that the bee stings are mainly local symptoms such as local redness, high skin temperature, and stinging pain; in severe cases, there can be chills, fever, dizziness, headache, nausea, vomiting, joint pain, palpitations, and even convulsions, coma or shock, or even systemic symptoms such as multi-organ failure. Our hospital had lost a young man last year because he was stung multiple times by a hornet’s nest and could not be resuscitated. The mechanism is hemolysis caused by the hemolytic toxin of bee venom, which leads to massive destruction of red blood cells, hemoglobin into the blood, blocking the renal tubules and causing renal insufficiency; treatment is to give glucocorticoid antitoxin, control the amount of fluid, diuresis to prevent renal tubular obstruction, if the red blood cell count is progressively decreasing and hemoglobinuria cannot be corrected, it should be performed as soon as possible. Hemodialysis should be performed as soon as possible. Emergency treatment of bee stings: 1. pull out the poisonous stinger, be careful not to squeeze the capsule when pulling out the bee stinger, you can use adhesive tape; 2. neutralize the toxin, local disinfection water (such as soap and water, hydrogen peroxide, medical ammonia, acetic acid) disinfection; 3. apply cold compresses to reduce swelling and pain, generally do not use ice directly on the wound. Prevention: 1. Ask professionals to remove bee nests near your home; 2. Try to wear long sleeves and long pants when outdoors, do not go barefoot or wear slippers, avoid wearing flowery or bright clothes and using perfumes and other items containing fragrances, and do not get stung by provoking irritated bees.