Patients with hyperlipidemia and coronary artery disease need oral lipid-regulating drugs. What are the representatives of lipid-regulating drugs, a large class of drugs with a wide variety? What are their characteristics? 1.Statin drugs This is the most commonly used lipid regulator, mainly used to reduce total cholesterol and LDL, the representative drugs are: atorvastatin, resulvastatin, lovastatin, pitavastatin, fluvastatin and so on. Atorvastatin and Rosuvastatin can be taken at any time of the day, while the others generally need to be taken at bedtime (because the body synthesizes cholesterol more vigorously at night). The main adverse effects of statins are hepatotoxicity and muscular adverse effects. However, it is generally safe to take under the guidance of a doctor. 2, fibrates mainly used for triglyceride elevation is obvious, the representative drugs are clofibrate, benzofibrate, fenofibrate, etc.. Caution is needed when combining fibrates with various drugs. Because of the increased risk of muscle adverse reactions when combined with statins or other fibrates, it is not recommended to use them together. 3.Nicotinic acid and its derivatives are mainly used for people with elevated triglycerides and lowered high-secretin lipoproteins, and are represented by niacin extended-release tablets and acipimox. For those who need to take long-term niacin lipid regulating drugs, blood lipid and liver and kidney function examination should be done regularly. 4.Ezetimibe is mainly used for people with elevated total cholesterol. It is a selective cholesterol absorption inhibitor, which can strongly inhibit the absorption of bile and dietary cholesterol in the small intestine. The only adverse effects of this drug are a small amount of gastrointestinal flatulence and diarrhea, which do not require special treatment. At the same time, long-term use does not affect the absorption of fat-soluble vitamins (A, D, E, K). 5.Bile acid chelators are a class of drugs that inhibit the reabsorption of cholesterol-rich bile acids and thus promote cholesterol excretion, representing drugs such as kolalenamide and kolalteb, which have been used sparingly due to many adverse reactions. 6, lipid antioxidants with lipid regulation and anti-lipid peroxidation effect, indications are hypercholesterolemia. The representative drug is probucol, which can be used alone or in combination with statins. 7.Fish oil is a kind of oil extracted from fatty fish. The main active ingredients are ω-3 polyunsaturated fatty acids, which have anti-inflammatory and lipid regulating effects. Currently confirmed effective is to lower triglycerides, but the effective dosage is uncertain, not clinically used as a routine drug.