Anemia in patients with acromegaly is the result of malnutrition. As the disease progresses, eating is affected by difficulty in swallowing and loss of appetite, leading to nutritional deficiencies and anemia. Acromegaly is a neurodegenerative disease with a progressive, chronic course. The disease will cause skeletal muscle weakness, accompanied by muscle fasciculation tremors, muscle atrophy, with the progression of the disease, will lead to medullary paralysis caused by dysphagia, but also accompanied by loss of appetite, etc. The patient will be due to insufficient intake of hematopoietic raw materials, such as vitamin B12, folic acid, iron, vitamin and so on deficiency and lead to anemia. Acromegaly can not be cured at present, can slow down the progress of the disease through treatment, can eat to give adequate nutrition, for serious dysphagia can consider percutaneous endoscopic gastrostomy to give nutritional supplements, anaemia can be given to replenish the blood of drugs, such as oral solution of ferrous gluconate, vitamin B12, etc. for treatment. Daily to closely observe the progress of the disease, if there are new symptoms to consult the doctor in time, do not self-medication.