Highly differentiated breast cancer is a kind of differentiation degree of breast cancer. Highly differentiated indicates that the cancer cells are more similar to normal cells, and this kind of cells grows slower compared with the cells of low-differentiated and moderately-differentiated breast cancer and is not prone to distant metastasis, so the prognosis of highly differentiated breast cancer is better. According to the specific clinical staging, the chances of tumor recurrence and metastasis are relatively low through comprehensive treatment such as surgery, chemotherapy, radiotherapy, targeted therapy and endocrine therapy. However, since it is a cancer, it should not be taken lightly, so regular review is needed after surgery to monitor whether the tumor has recurred and metastasized, and through regular review, it is also possible to find out whether there is any primary tumor on the opposite side of the breast in time.