For the early stage of atherosclerosis disease only show outstanding patients, most of them almost do not have any other clinical symptoms, are in the state of latent development under the hidden evil thought. For patients with medium-term atherosclerosis disease, most of them have more or less clinical symptoms such as palpitation, panic, chest pain, chest tightness, headache, dizziness, cool and numb limbs, sore and lazy limbs, claudication, reduced vision, memory loss, insomnia and dreaminess, etc. Different patients will have different symptoms. Aortic atherosclerosis, most of the non-specific symptoms percussion can be found in the widening of the aortic turbid zone behind the sternal stalk; the second heart sound in the aortic valve area is hyperactive with metallic tone, and there is a systolic murmur. The aortic node can be seen on X-ray as a dilated and distorted aorta projecting to the upper left, and sometimes a patchy or arc-shaped intra-plaque calcium deposit shadow can be seen. Aortic atherosclerosis can also form aortic aneurysms occurring most commonly in the abdominal aorta below the opening of the renal artery, followed by the aortic arch and descending aorta. Coronary atherosclerosis can cause angina pectoris, myocardial infarction, and myocardial fibrosis. Cerebral atherosclerosis, cerebral ischemia can cause symptoms such as vertigo, headache and fainting. Cerebral artery thrombosis or rupture and bleeding can cause cerebrovascular accident, with headache and vertigo, vomiting, sudden loss of consciousness, paralysis, hemianopia or aphasia, etc. When cerebral atrophy causes dementia, there are symptoms such as psychopathy, action disorder, intellectual and memory loss and even complete personality change. Renal atherosclerosis, clinically uncommon can cause intractable hypertension, the year in 55 years of age or more and suddenly occur. If you have hypertension, you should consider the possibility of this disease such as renal artery thrombosis, which can cause pain in the kidney area, urinary closure and fever. Atherosclerosis of mesenteric arteries may cause dyspepsia, decreased bowel tone, constipation and abdominal pain. In thrombosis, there is severe abdominal pain, abdominal distension and fever. In case of intestinal wall necrosis, it may cause symptoms such as blood in the stool, paralytic intestinal obstruction and shock. Atherosclerosis of the extremities is more common in the lower extremities, especially in the leg arteries due to impaired blood supply, causing coldness, numbness and intermittent claudication in the lower extremities, i.e., numbness and pain or even spasm in the gastrocnemius muscle when walking, which disappears after rest and appears again when walking again; in severe cases, there may be persistent pain in the arteries of the lower extremities, especially the dorsalis pedis artery pulsation is weak or disappears. Gangrene can occur when the arterial lumen is completely occluded.