Atherosclerosis and its complications are currently the number one cause of death in both China and developed Western countries. Worldwide, atherosclerosis thrombosis accounts for 52% of all deaths, far surpassing tumors (24%), which are the second leading cause of death. So what is atherosclerosis? Atherosclerosis is a systemic disorder. It occurs mainly in the large and medium-sized arteries throughout the body, mainly due to the narrowing or occlusion of the arterial cavity causing various clinical manifestations of organ and tissue ischemia. Causes and mechanisms: It is not completely clear that hyperlipidemia hypertension smoking diabetes obesity and other predisposing factors Arteriosclerosis occlusive disease with different parts of the blocked blood vessels can be divided into the following: 1, coronary artery sclerosis (coronary heart disease): if the diameter of the narrowing of more than 70%, it is possible to occur at any time angina, myocardial infarction, arrhythmia, and even sudden cardiac death. 2, lower extremity atherosclerosis, early symptoms are mainly manifested as intermittent claudication, simply put, that is, can not walk. The disease progresses to the late stage of pain at rest is a manifestation of severe ischemia of the lower limbs, often accompanied by numbness of the extremities, dorsal foot artery pulsation disappeared. Ulceration and gangrene of the extremity may also occur in advanced stages. In the end stage of the disease, amputation is often required. The mortality rate of amputation in patients with atherosclerosis is high (30-40%). Patients with intermittent claudication have a mortality rate of 10%-15% if left untreated for 5 years, and patients with severe lower limb ischemia have a mortality rate of nearly 25% if left untreated for 1 year. 3, carotid artery sclerosis stenosis, can cause cerebral ischemia (including temporary ischemic attack), cerebral atrophy, or cause cerebrovascular rupture and bleeding. Early stages of cerebral arteriosclerosis: dizziness, dizziness, headache, tinnitus, drowsiness, memory loss, easy fatigue, emotional abnormalities (emotional agitation, lack of self-control, and as the disease worsens, it will gradually become indifferent to expressions and lack of interest in surrounding things), low judgment (manifested by the inability to hold and focus attention, reduced imagination, and relying on others for assistance in handling problems). In the middle and late stages of cerebral arteriosclerosis, stiff gait or unstable walking, dementia, seizure-like spasms, and in severe cases, cerebral infarction, cerebral hemorrhage or even sudden death. 4, renal artery stenosis, often causing nocturnal urination, intractable hypertension, serious cases may have renal insufficiency, and eventually kidney atrophy and necrosis. 5, mesenteric artery atherosclerosis, can be manifested as abdominal pain after a full meal, blood in the stool and other symptoms.