Alzheimer’s dementia, how much do you know? According to statistics, the prevalence of vascular dementia in our population over 60 years old is 324/100,000 population, while the prevalence of Alzheimer’s disease dementia is 238/100,000 population. It is expected that by 2025, the prevalence of Alzheimer’s disease dementia is 22 million people worldwide. Alzheimer’s disease dementia, as the main type of dementia in old age, is the fourth leading cause of death after heart disease, cancer and stroke. Alzheimer’s disease brings a great burden to the society and families, 80% of the patients are accompanied by mental abnormality, 50% of the patients have aggressive behavior, so the prevention and treatment of Alzheimer’s disease dementia has attracted extensive attention from the medical profession and even the whole society. Alzheimer’s disease dementia, including Alzheimer’s disease, vascular dementia and mixed dementia. It is a progressive development of fatal neurodegenerative diseases, clinical manifestations of cognitive function and memory deterioration, progressive decline in daily life ability, and a variety of neuropsychiatric symptoms and behavioral disorders. The clinical symptoms of Alzheimer’s disease dementia are categorized into two aspects, namely, memory loss, cognitive impairment and psychiatric symptoms. According to the development of the disease and the severity of cognitive deficits, they can be categorized as mild, moderate and severe. 1, mild: memory impairment of recent events is often the first and most obvious symptoms, such as: the words just said, just done things can not be recalled, often lost items; learning new things is difficult, reading books and newspapers can not be recalled after reading the content of them. Often have time orientation disorder, the patient can not remember the specific year, month and day. Calculation ability decreases and it is difficult to complete simple calculations. Delayed thinking, difficult to think of problems, but can complete familiar daily tasks or routine. The patient can basically take care of himself/herself in his/her personal life. Personality changes often appear in the early stages of the disease, the patient becomes lack of initiative, reduced activity, loneliness, selfishness, reduced interest in the surrounding environment, more indifferent to the people around them, or even indifferent to their loved ones, emotionally unstable, irritable. It is difficult to adapt to the new environment. 2. Moderate: manifested by increasingly serious memory loss, used items are forgotten, daily necessities are lost. The memory of things that have just happened is also forgotten. Long-term memory is also impaired, unable to recall their own work experience, even do not know their own year of birth, forget their home address and the names of friends and relatives, but can still remember their own names. Sometimes there are misrepresentations and fictions due to memory loss. There is disorientation, easy to get lost and can not find the way home. There is speech dysfunction, speech is disorganized and empty, cannot list the names of similar items, and does not recognize one’s relatives and friends. Disuse is manifested by the inability to properly express themselves with gestures and the inability to make continuous movements, such as brushing their teeth. The patient is no longer able to work and has difficulty in completing household chores, and even basic household chores such as washing and dressing require supervision or assistance from family members. The patient’s spirit and behavior is also more prominent, mood swings unstable; or because they can not find their own placed items, and suspected of being stolen by others, or because of strong jealousy and suspected of spousal infidelity, which may be accompanied by fragmentary hallucinations; sleep disorders, some patients are restless at night, thinking of sleep during the day. Behavioral disorders hide dirt; take other people’s things; or manifested as instinctive hyperactivity, public nudity, and sometimes aggressive behavior. 3. Severe: memory, thinking and other cognitive functions are impaired. The patient forgets his/her name and age, and does not recognize his/her relatives. The patient’s language ability further deteriorates as he/she only speaks spontaneously, with monotonous content or repeated unintelligible sounds, and eventually loses his/her language function. The patient’s activities are gradually reduced, and gradually lose the ability to walk, or even can not stand, and ultimately can only be bedridden, incontinence. Prevention of dementia in old age is mainly in the following aspects: 1. Improve the working environment. A pleasant and easy living and working environment is conducive to good health. 2.Limit alcohol and quit smoking. Excessive drinking will lead to abnormal brain function People who drink more than 0.3 liters of alcohol a day are more prone to cerebrovascular dementia than the general public, and it is advocated that the daily alcohol consumption should not be more than 1-2 taels. Smoking is the cause of cerebrovascular dementia and myocardial infarction and other diseases independent risk factors, quit smoking is good for physical and mental health. 3.Prevention of arteriosclerosis Reduce weight, control hypertension and diabetes and other diseases that promote arteriosclerosis. 4, dietary regulation: to prevent the intake of high-fat food caused by cholesterol, intake of essential nutrients, such as protein, inorganic salts, amino acids and vitamins, especially vitamin B1, B2 and B6, vitamin C and vitamin E is very important for the elderly, such as half a catty of fruits, half a catty of vegetables, 2-3 two lean meats or fish and so on, an egg every day. 5, to maintain a happy spirit is conducive to longevity and mental health. 6, to organize life and learning: in old age, but also insist on learning new knowledge, to maintain extensive contact with society. 7, after retirement, to have a rich life content, a wide range of interests and hobbies, these can promote brain activity, but also can slow down or reduce the aging process. 8, regular physical examination, early detection and treatment of physical diseases, to their own bodies both to pay attention to, but not overly worried. 9, often participate in activities: continuous, slower movement, such as walking, jogging, gymnastics, tai chi and so on. 10.For moderate to severe dementia, medication can take donepezil and meperidine.