Bilirubin is divided into total bilirubin, indirect bilirubin and direct bilirubin, and the sum of indirect bilirubin and direct bilirubin values is equal to total bilirubin, so there are several cases of high bilirubin: 1. 2, elevated total bilirubin, mainly elevated direct bilirubin, is obstructive jaundice, mostly suggesting biliary obstruction, and should be investigated by hepatobiliary imaging; 3, elevated total bilirubin, mainly elevated indirect bilirubin, is hemolytic jaundice, suggesting possible hemolytic anemia, and should be investigated by routine blood tests, reticulocytes, etc. 4, mildly increased bilirubin, less than 2 times the normal line, or No clinical significance, or related to certain metabolic factors, however, no drug intervention is required.