Quick pain relief for children with toothaches at night can be provided by cold compresses, salt water mouth rinses, and medication. 1. Cold compress: children in the middle of the night toothache may be due to gum swelling, inflammation, etc., resulting in high pressure in the teeth, nerve pain, you can use ice cubes or wet towels to reduce the temperature through the method of cold compresses, reduce the pressure in the teeth, relieve tooth pain. 2. Salt water gargling: Salt water has a certain disinfectant and sterilization effect, gargling with salt water can inhibit some oral bacteria and relieve tooth pain. 3. medication: children’s midnight toothache may be due to pulpitis, periodontitis and other diseases, you can use metronidazole, ibuprofen and other drugs under the guidance of the doctor to relieve tooth pain. Children’s night toothache can not be relieved, it is recommended to go to the hospital dental emergency department for examination and treatment.