Eye pain from crying can be treated with recombinant human epidermal growth factor drops or recombinant bovine basic fibroblast growth factor drops or by applying hot and cold compresses to relieve discomfort. Painful crying eyes may be caused by wiping tears and rubbing the eyes while crying, resulting in corneal epithelial abrasions, or prolonged crying, eye congestion and edema, and prolonged tension of the eye muscles, which causes pain. Corneal epithelial abrasions need to point to promote the repair of eye drops treatment, can accelerate the healing of the damaged corneal epithelium, relieve pain, such as commonly used recombinant human epidermal growth factor eye drops or recombinant bovine alkaline fibroblast growth factor eye drops and so on. For pain caused by eye congestion and edema, cold compresses are usually applied first to lower the local tissue temperature, thus reducing the sensitivity of pain-sensing nerve fibers and relieving pain symptoms, and hot compresses are applied after a period of time to promote recovery. Drugs need to be applied under the guidance of a doctor, do not self-medication.