The normal value of mean erythrocyte volume is 86-100 fl. High mean erythrocyte volume refers to a mean erythrocyte volume greater than 100 fl. Mean erythrocyte volume plays an important role in the diagnosis and treatment of various anemic diseases. High mean erythrocyte volume is divided into physiological and pathological causes: 1. Physiological causes: Physiological high mean erythrocyte volume is mostly seen in newborns, pregnancy, after taking oral contraceptives or drinking alcohol, etc. This condition usually does not require special treatment; 2. Pathological causes: Pathological high mean erythrocyte volume often occurs in diseases caused by vitamin B12 and folic acid deficiency, such as megaloblastic anemia, nutritional megaloblastic anemia, etc. In case of high mean red blood cell volume, further examination is recommended to identify the cause of the disease and treat the cause, supplementation with vitamin B12 and folic acid under the guidance of a doctor, and regular review to monitor the recovery. Note: Usually you can take some folic acid tablets and vitamin B12 to correct anemia, and you can also eat some blood-supplementing foods, such as red dates and gum, foods rich in folic acid, such as nuts, beans, vegetables and fruits, and foods rich in vitamin B12, such as animal liver, milk, eggs, etc.