Mean red blood cell volume refers to the average volume of individual red blood cells in the human body, with a normal value of 86-100 fl. Low mean red blood cell volume refers to the volume of individual red blood cells in the human body being lower than 86 fl, which is smaller than the normal red blood cells. Low mean red blood cell volume is commonly found in iron deficiency anemia and thalassemia: I. Iron deficiency anemia: 1. Cause: Due to the decrease of iron in the body of iron deficiency anemia patients, resulting in red blood cells can not synthesize hemoglobin normally, low hemoglobin in the blood, thus causing low mean red blood cell volume; 2. Treatment: Iron supplements can be taken under the guidance of a doctor, and you can usually eat some pig’s blood, spinach and other foods, which can also The effect of iron supplementation. Thalassemia: 1. Causes: Thalassemia patients have impaired synthesis of peptide chains in the body, resulting in the inability to synthesize hemoglobin normally in the blood, which results in low average red blood cell volume in the body; 2. Treatment: Folic acid and vitamin B12 can be supplemented appropriately, and blood transfusion therapy can be performed if necessary. The average red blood cell volume plays an important role in the diagnosis and treatment of various anemic diseases. It is recommended to go to the hospital to check hemoglobin, red blood cells, serum iron as well as vitamin B12 and folic acid to determine whether the disease is anemia or other diseases, so that the disease can be detected and treated early to avoid delays.